1.
Indian J Cancer
;
1991 Sep; 28(3): 119-23
Article
in English
| IMSEAR
| ID: sea-50596
ABSTRACT
The use of cytotoxic drugs has improved the survival figures in malignancies. These drugs exert harmful effects on the tumour cell and normal cells as well. The detrimental effects on gonads were studied in 36 patients who had cytotoxic chemotherapy for various malignancies. In Group I (20 adults in clinical remission after chemotherapy), sterility was noted in 93.7% of men and hundred percent of women experienced irregularly mensus during treatment, 50% of them subsequently developing persistent amenorrhoea. In Group II, (16 adults undergoing chemotherapy) 100% of men had oligospermia, with 75% of them developing azoospermia after 2-3 cycles of treatment. Women also showed similar effect, but were less vulnerable than men.
Subject(s)
Adolescent , Adult , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Female , Humans , Male , Menstruation Disturbances/chemically induced , Middle Aged , Neoplasms/drug therapy , Oligospermia/chemically induced , Ovary/drug effects , Testis/drug effects
2.
Indian J Cancer
;
1987 Jun; 24(2): 99-106
Article
in English
| IMSEAR
| ID: sea-50326
3.
J Indian Med Assoc
;
1982 Aug; 79(3): 27-9
Article
in English
| IMSEAR
| ID: sea-101451
Subject(s)
Adolescent , Adult , Busulfan/therapeutic use , Child , Child, Preschool , Drug Resistance , Female , Humans , Infant , Infant, Newborn , Leukemia, Myeloid/drug therapy , Male , Middle Aged , Spleen/radiation effects
4.
Indian J Ophthalmol
;
1979 Apr; 27(1): 23-4
Article
in English
| IMSEAR
| ID: sea-71231
Subject(s)
Adult , Breast Neoplasms , Carcinoma/secondary , Eye Neoplasms/secondary , Female , Humans , Oculomotor Muscles
5.
J Indian Med Assoc
;
1968 Jun; 50(12): 567-71
Article
in English
| IMSEAR
| ID: sea-95876
6.
Indian J Cancer
;
1967 Jun; 4(2): 151-3
Article
in English
| IMSEAR
| ID: sea-50829
7.
Indian J Cancer
;
1965 Dec; 2(4): 185-92
Article
in English
| IMSEAR
| ID: sea-49808